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COPD Causes and Risk Factors

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Each year, nearly 10 million adults are diagnosed with chronic obstructive pulmonary disease (COPD). However, many people with COPD go undiagnosed and untreated. In order to understand your chances of getting COPD, it is important to understand the disease's causes and risk factors.

COPD Causes

Many people who have COPD also have one of the following:

COPD can also be caused by a rare genetic order, alpha-1-antitrypsin deficiency, which can cause shortness of breath, wheezing and lung infections.

COPD and Smoking

Most experts in the medical community agree that the primary cause of COPD is long-term smoking. In fact, studies have shown that 90 percent of COPD cases in the United States are linked to cigarette smoking in some way. An estimated 15 percent of smokers will develop COPD at some point in their lifetime.

Cigarette smoke damages the lungs in various ways. Inflammation in the lungs is caused by cigarette smoke, and smoking also stimulates cells to release elastase, an enzyme that breaks down the elastic fibers in lung tissue.

Cigarette smoking is not the only smoking-related cause of COPD. Cigar smoke and pipe smoke also contribute to COPD.

COPD Risk Factors

There are many risk factors have been linked COPD, including:

Resources

A.D.A.M. Inc. (2005).COPD Risk Factors. Retrieved July 29, 2007, from the About.com Web site: http://lungdiseases.about.com/od/riskfactor1/a/riskfactorsCOPD.htm.

Mayo Clinic Staff (2007). COPD. Retrieved July 29, 2007, from the Mayo Clinic Web site: http://mayoclinic.com/health/copd/DS00916/DSECTION=3.

MedicineNet, Inc. (2006). Chronic Obstructive Pulmonary Disease. Retrieved July 29, 2007, from the MedicineNet.com Web site: http://www.medicinenet.com/chronic_obstructive_pulmonary_disease_copd/article.htm#2howdoes.

National Heart Blood and Lung Institute (2007). What Causes COPD? Retrieved July 29, 2007, from the National Heart Lung Blood Institute Web site: http://www.nhlbi.nih.gov/health/dci/Diseases/Copd/Copd_Causes.html.